I've never blocked off the power valve for tuning. I've never read doing it that way anywhere, except on some drag-only setups. I understand they're saying block it off temporarily, and I guess I see what they're trying to accomplish, but I have no experience doing it that way. The power valve has a number stamped on it, which tells you at what vacuum point it opens (and therefore provides enrichment). So if your power valve has a 65 stamped on it, it will open at 6.5 inches of vacuum. Using your vacuum gauge + WB02 while driving, you should be able to tell when it opens.
*) Get your ignition timing set before starting anything with the carb. Vacuum advance should be utilized, and it should run off manifold vacuum, NOT ported vacuum.
*) With the engine fully warmed up, start with your idle mixture screws. Put the car in gear, and have someone hold the brakes. Adjust screws, in even amounts, to achieve highest vacuum. Usually 1/4 turn at a time. If idle gets too low/high, adjust idle-speed screw as needed. Closing the mixtures screws should make it leaner, opening the screws should make it richer. If you turn the screws all the way closed and the engine doesn't stall, you're getting fuel from somewhere else. I'd close them at the very beginning just as a sanity-check and make sure it stalls. 1.5-2 turns open should be a good starting point.
The Holleys I've been successful with only had idle mixture screws on the primary side. I struggled with Tony's carb that had 4-corner idle circuits. 4 corner idles doesn't make sense to me, especially on a vacuum secondary carb.
*) Once idle mixture is done, go for a drive. Light throttle, keep out of the power valve. Lean out the primaries till you get lean-stumbles on light throttle, then go back up +2 jet sizes.
*) Adjusting the secondary jets is probably best accomplished at a dragstrip. (or dyno) Make adjustments +/- 2 jet sizes at a time. Adjust for highest MPH. (or HP on dyno) I've never tuned a carb with a WB02, so you could also try adjusting to shoot for 12.5-12.8 AFR @ WOT.
*) You mentioned you have a vacuum secondary, which means there is a diaphragm on the passenger side that controls the opening-rate of the secondaries. The springs are color coded. From fastest-opening to slowest-opening: white, short-yellow, tall-yellow, purple, plain, brown, black. Use the fastest opening spring that doesn't cause a bog. The plain spring (no color) is 'stock'. I'd start with purple or tall-yellow,
All of this takes a lot of trial and error. A session at the chassis dyno will make it a lot quicker. But you and Walt are both retired, so you should have plenty of time...

(I say that out of envy!)
I didn't mention the power valve. I'm not real certain how to decide on correct selection for that. I think if you find yourself giving it more throttle than what you think you need for part-throttle driving, go to a bigger number power valve. This will open it sooner.
All of this trial-and-error stuff is why self-tuning EFI is so popular. However, it has a higher up-front cost and is more work to do the initial install. Fuel delivery is *critical*, and I cannot emphasize this point enough. It may also require some manual tweaking, but it will be done with an electronic controller or laptop instead of wrenchs/screwdrivers. But once it's working, it's great.
-Dave